Department of Cellular Differentiation

Institute for Frontier Medical Sciences

We are aiming at the elucidation of molecular interactions and signaling networks underlying cartilage, bone and vascular formation.

Our current research efforts are focused on the following studies: (1) Action mechanisms of mesenchyme-derived anti-angiogenesis factors and their therapeutic applications for angiogenic diseases; (2) Molecular mechansims of vascular regression and angiogenesis during chicken embryogenesis; (3) Vascular development and chondrogenesis in fish; (4) Molecular mechanisms of chondrogenic differentiation; (5) Molecular mechanisms of tendogenesis/ligamentogenesis; (6)Molecular mechanisms of cartilage regeneration; (7) Functional analysis of chondromodulin-II.